L-Homocystine ( —— )

Catalog No. M19719 CAS No. 626-72-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

L-Homocystine
Note

Research use only not for human use.
Brief Description

Homocystine is the double-bonded form of homocysteine but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an elevation of homocysteine in schizophrenia.
Description

Homocystine is the double-bonded form of homocysteine but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an elevation of homocysteine in schizophrenia. It has been demonstrated that neural tube defects are related to a genetic defect in homocysteine metabolism. Sufficient intake of folic acid is believed to reduce this risk by enhancing methylation of homocysteine and its conversion to methionine thereby compensating for this genetic defect (homocystinuria). Plasma homocysteine levels are elevated when folate levels are in the lower half of the normal range.
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Human Endogenous Metabolite
Research Area

——
Indication

——

CAS Number

626-72-2
Formula Weight

268.35
Molecular Formula

C8H16N2O4S2
Purity

>98% (HPLC)
Solubility

DMSO: 1 mg/mL (3.73 mM; ultrasonic and adjust pH to 5 with HCl); H2O: 1 mg/mL (3.73 mM; ultrasonic and adjust pH to 2 with HCl)
SMILES

N[C@@H](CCSSCC[C@H](N)C(O)=O)C(O)=O
Chemical Name

——

1.Carson N A J Dent C E Field C M B et al. Homocystinuria: Clinical and pathological review of ten cases[J]. Journal of Pediatrics 1965 66(3).

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