L-Homocystine

CAS No. 626-72-2

L-Homocystine ( —— )

Catalog No. M19719 CAS No. 626-72-2

Homocystine is the double-bonded form of homocysteine but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an elevation of homocysteine in schizophrenia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    L-Homocystine
  • Note
    Research use only not for human use.
  • Brief Description
    Homocystine is the double-bonded form of homocysteine but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an elevation of homocysteine in schizophrenia.
  • Description
    Homocystine is the double-bonded form of homocysteine but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an elevation of homocysteine in schizophrenia. It has been demonstrated that neural tube defects are related to a genetic defect in homocysteine metabolism. Sufficient intake of folic acid is believed to reduce this risk by enhancing methylation of homocysteine and its conversion to methionine thereby compensating for this genetic defect (homocystinuria). Plasma homocysteine levels are elevated when folate levels are in the lower half of the normal range.
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    626-72-2
  • Formula Weight
    268.35
  • Molecular Formula
    C8H16N2O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 1 mg/mL (3.73 mM; ultrasonic and adjust pH to 5 with HCl); H2O: 1 mg/mL (3.73 mM; ultrasonic and adjust pH to 2 with HCl)
  • SMILES
    N[C@@H](CCSSCC[C@H](N)C(O)=O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Carson N A J Dent C E Field C M B et al. Homocystinuria: Clinical and pathological review of ten cases[J]. Journal of Pediatrics 1965 66(3).
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