L-BUTHIONINE-(SR)-SULFOXIMINE ( L-Butionine sulfoximine )

Catalog No. M20128 CAS No. 83730-53-4

L-Buthionine-(SR)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
50MG	42	In Stock
100MG	72	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

L-BUTHIONINE-(SR)-SULFOXIMINE
Note

Research use only not for human use.
Brief Description

L-Buthionine-(SR)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.
Description

L-Buthionine-(SR)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.
Synonyms

L-Butionine sulfoximine
Pathway

Others
Target

Other Targets
Recptor

γ-glutamylcysteine synthetase
Research Area

——
Indication

——

Chemical Information

CAS Number

83730-53-4
Formula Weight

222.31
Molecular Formula

C8H18N2O3S
Purity

>98% (HPLC)
Solubility

H2O:41.67 mg/mL (187.44 mM; Need ultrasonic)
SMILES

CCCCS(=N)(=O)CC[C@H](N)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Fruehauf JP et al. Selective and synergistic activity of L-SR-buthionine sulfoximine on malignant melanoma is accompanied by decreased expression of glutathione-S-transferase. Pigment Cell Res. 1997 Aug;10(4):236-49.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks