KPT-6566

CAS No. 881487-77-0

KPT-6566 ( —— )

Catalog No. M20699 CAS No. 881487-77-0

KPT-6566 is a novel selective covalent pin1 inhibitor KPT-6566 shows an IC50 of 640?nM and a Ki of 625.2 nM for PIN1 PPIase domainand has anti-cancer activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 133 In Stock
5MG 267 In Stock
10MG 410 In Stock
25MG 678 In Stock
50MG 954 In Stock
100MG 1287 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    KPT-6566
  • Note
    Research use only not for human use.
  • Brief Description
    KPT-6566 is a novel selective covalent pin1 inhibitor KPT-6566 shows an IC50 of 640?nM and a Ki of 625.2 nM for PIN1 PPIase domainand has anti-cancer activity.
  • Description
    KPT-6566 is a novel selective covalent pin1 inhibitor KPT-6566 shows an IC50 of 640?nM and a Ki of 625.2 nM for PIN1 PPIase domainand has anti-cancer activity.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PIN1 PPIase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    881487-77-0
  • Formula Weight
    443.5
  • Molecular Formula
    C22H21NO5S2??
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:120 mg/mL?(270.55 mM)
  • SMILES
    CC(C)(C)c1ccc(cc1)S(=O)(=O)\N=C1/C=C(SCC(O)=O)C(=O)c2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang J Zhao F Yu X et al. Pharmacokinetics of eupalinolide A eupalinolide B and hyperoside from Eupatorium lindleyanum in rats by LC/MS/MS[J]. Journal of Chromatography B 2015 995-996:1-7.
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