KN1022

CAS No. 205255-11-4

KN1022( —— )

Catalog No. M35326 CAS No. 205255-11-4

KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 178 Get Quote
5MG 255 Get Quote
10MG 374 Get Quote
25MG 545 Get Quote
50MG 762 Get Quote
100MG 1017 Get Quote
500MG 2034 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    KN1022
  • Note
    Research use only, not for human use.
  • Brief Description
    KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.
  • Description
    KN1022 an inhibitor of phosphorylation of platelet-derived growth factor receptor (PDGFR) with IC50 of 0.24 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PDGFR
  • Recptor
    PDGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    205255-11-4
  • Formula Weight
    438.44
  • Molecular Formula
    C21H22N6O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(C)C1=CC=2C(=NC=NC2C=C1OC)N3CCN(C(NC4=CC=C(N(=O)=O)C=C4)=O)CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kenji Matsuno, et al. Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives. J Med Chem. 2002 Jul 4;45(14):3057-66.?
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