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KKI-5
CAS No. 97145-43-2
KKI-5( —— )
Catalog No. M30490 CAS No. 97145-43-2
KKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 158 | Get Quote |
|
| 10MG | 284 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameKKI-5
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NoteResearch use only, not for human use.
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Brief DescriptionKKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.
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DescriptionKKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.(In Vitro):The KKI-5 Peptide corresponds to aa386-391 of bovine kininogen-1 that encompasses the aa388-389 kallikrein proteolytic site. The synthetic KKI-5 can attenuate breast cancer cell invasion, therefore it is investigated for its role in invasion and metastasis of cancer cells.
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In VitroThe KKI-5 Peptide corresponds to aa386-391 of bovine kininogen-1 that encompasses the aa388-389 kallikrein proteolytic site. The synthetic KKI-5 can attenuate breast cancer cell invasion, therefore it is investigated for its role in invasion and metastasis of cancer cells.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorKallikrein Inhibitor
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Research Area——
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Indication——
Chemical Information
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CAS Number97145-43-2
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Formula Weight773.88
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Molecular FormulaC35H55N11O9
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:Ac-Pro-Phe-Arg-Ser-Val-Gln-NH2
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Deshpande MS, et al. Mapping the binding site of tissue kallikrein: preparation and testing of all possible substrate analog inhibitors homologous with the sequence of kininogen between Ser386 and Gln392. J Med Chem. 1992 Aug 21;35(17):3094-102.
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