KB-R7943

CAS No. 182004-65-5

KB-R7943 ( KB-R7943 mesylate )

Catalog No. M20553 CAS No. 182004-65-5

KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 45 In Stock
10MG 58 In Stock
25MG 118 In Stock
50MG 212 In Stock
100MG 320 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    KB-R7943
  • Note
    Research use only not for human use.
  • Brief Description
    KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.
  • Description
    KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.
  • Synonyms
    KB-R7943 mesylate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Na+/Ca2+ Exchanger
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    182004-65-5
  • Formula Weight
    427.5
  • Molecular Formula
    C17H21N3O6S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:27 mg/mL (63.16 mM)
  • SMILES
    CS(O)(=O)=O.NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+]([O-])=O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Brustovetsky T Brittain M K Sheets P L et al. KB-R7943 an inhibitor of the reverse Na+ /Ca2+ exchanger blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I.[J]. British Journal of Pharmacology 2015 162(1):255-270.
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