KB-R7943 ( KB-R7943 mesylate )

Catalog No. M20553 CAS No. 182004-65-5

KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

KB-R7943
Note

Research use only not for human use.
Brief Description

KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.
Description

KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.
Synonyms

KB-R7943 mesylate
Pathway

Others
Target

Other Targets
Recptor

Na+/Ca2+ Exchanger
Research Area

——
Indication

——

Chemical Information

CAS Number

182004-65-5
Formula Weight

427.5
Molecular Formula

C17H21N3O6S2
Purity

>98% (HPLC)
Solubility

DMSO:27 mg/mL (63.16 mM)
SMILES

CS(O)(=O)=O.NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+]([O-])=O)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Brustovetsky T Brittain M K Sheets P L et al. KB-R7943 an inhibitor of the reverse Na+ /Ca2+ exchanger blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I.[J]. British Journal of Pharmacology 2015 162(1):255-270.

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