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KAN0438757

CAS No. 1451255-59-6

KAN0438757( —— )

Catalog No. M23618 CAS No. 1451255-59-6

KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    KAN0438757
  • Note
    Research use only, not for human use.
  • Brief Description
    KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.
  • Description
    KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Glucokinase
  • Recptor
    PFKFB3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1451255-59-6
  • Formula Weight
    447.43
  • Molecular Formula
    C21H18FNO7S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:130 mg/mL (290.55 mM; Need ultrasonic)
  • SMILES
    C1=CC(=CC(=C1)S(=O)(=O)NC2=CC(=C(C=C2)C(=O)OCCO)O)C3=C(C=CC(=C3)F)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gustafsson NMS, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018 Sep 24;9(1):3872.
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