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JZP-430

CAS No. 1672691-74-5

JZP-430 ( —— )

Catalog No. M23752 CAS No. 1672691-74-5

JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    JZP-430
  • Note
    Research use only, not for human use.
  • Brief Description
    JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM).
  • Description
    JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MAGL
  • Recptor
    ABHD6
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1672691-74-5
  • Formula Weight
    354.5
  • Molecular Formula
    C16H26N4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:90 mg/mL?(253.9 mM;?Need ultrasonic)
  • SMILES
    CN(C1CCCCCCC1)C(Oc1nsnc1N1CCOCC1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Patel JZ, et al. Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. ChemMedChem. 2015 Feb;10(2):253-65.
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