JZL195

CAS No. 1210004-12-8

JZL195 ( JZL195; JZL-195; JZL 195 )

Catalog No. M17194 CAS No. 1210004-12-8

JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 59 In Stock
25MG 125 In Stock
50MG 237 In Stock
100MG 356 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    JZL195
  • Note
    Research use only, not for human use.
  • Brief Description
    JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.
  • Description
    JZL195 is a potent and selective dual inhibitor of FAAH and monacylglycerol lipase (MAGL). JZL195 has greater anti-allodynic efficacy than selective FAAH, or MAGL inhibitors, plus a greater therapeutic window than a cannabinoid receptor agonist. JZL195 may have greater potential in alleviating neuropathic pain, compared to selective FAAH and MAGL inhibitors, or cannabinoid receptor agonists.
  • Synonyms
    JZL195; JZL-195; JZL 195
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    FAAH; MAGL
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    1210004-12-8
  • Formula Weight
    433.46
  • Molecular Formula
    C24H23N3O5
  • Purity
    98%
  • Solubility
    DMSO : ≥ 42 mg/mL. 96.89 mM
  • SMILES
    [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cc(Oc4ccccc4)ccc3)CC2)cc1
  • Chemical Name
    4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Long JZ, et al. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20270-5.
molnova catalog
related products
  • Phenothrin

    Phenothrin, also called sumithrin, is a synthetic pyrethroid that kills adult fleas and ticks. It has also been used to kill head lice in humans.

  • Lupetidin

    2,6-Dimethylpiperidines are chemical compounds with the formula C5H8(CH3)2NH. Three stereoisomers exist: the achiral (R,S)-isomer and the chiral (R,R)/(S,S) enantiomeric pair. Dimethylpiperidines are derivatives of the heterocycle piperidine, wherein two hydrogen atoms are replaced by methyl groups.

  • Hemicholinium-3(b)

    A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system.