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JUN04542

CAS No. 2367004-54-2

JUN04542( CL-092 )

Catalog No. M24079 CAS No. 2367004-54-2

JUN04542 is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 110 In Stock
10MG 177 In Stock
25MG 410 In Stock
50MG 605 In Stock
100MG 860 In Stock
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Biological Information

  • Product Name
    JUN04542
  • Note
    Research use only, not for human use.
  • Brief Description
    JUN04542 is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
  • Description
    JUN04542 is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Rat Dosage:3 mg/kg (Pharmacokinetic Analysis) Administration:IV Result:Had a T1/2 of 5.4 hours, a CL of 43 mL/hr?kg.
  • Synonyms
    CL-092
  • Pathway
    Angiogenesis
  • Target
    c-Met/HGFR
  • Recptor
    Axl|c-Met|KDR|Mer
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2367004-54-2
  • Formula Weight
    528.53
  • Molecular Formula
    C29H25FN4O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lynne Canne Bannen, Minna Bui, Faming Jiang, et al Compounds for the treatment of kinase-dependent disorders;WO 2019148044
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