JR14a

CAS No. 2411440-41-8

JR14a ( 5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride )

Catalog No. M24104 CAS No. 2411440-41-8

JR14a is a potent antagonist of human complement C3a receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 178 In Stock
10MG 282 In Stock
25MG 480 In Stock
50MG 691 In Stock
100MG 972 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    JR14a
  • Note
    Research use only, not for human use.
  • Brief Description
    JR14a is a potent antagonist of human complement C3a receptor.
  • Description
    JR14a is a potent antagonist of human complement C3a receptor.
  • Synonyms
    5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    C3a
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2411440-41-8
  • Formula Weight
    533.5
  • Molecular Formula
    C25H26Cl2N4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 90 mg/mL?(168.71 mM;?Need ultrasonic)
  • SMILES
    Cc1c(C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)sc(C(c(cc2)ccc2Cl)c(cc2)ccc2Cl)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rowley JA, et, al. Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity. J Med Chem. 2020 Jan 23;63(2):529-541.
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