Cart
sales@molnova.com
JNK-IN-13
CAS No. 345986-38-1
JNK-IN-13( —— )
Catalog No. M37058 CAS No. 345986-38-1
JNK-IN-13 is a selective and potent JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 31 | Get Quote |
|
| 25MG | 48 | Get Quote |
|
| 50MG | 78 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameJNK-IN-13
-
NoteResearch use only, not for human use.
-
Brief DescriptionJNK-IN-13 is a selective and potent JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.
-
DescriptionJNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMAPK/ERK Signaling
-
TargetJNK
-
RecptorJNK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number345986-38-1
-
Formula Weight286.74
-
Molecular FormulaC13H7ClN4S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : ≥ 31 mg/mL (108.11 mM )
-
SMILESClc1nccc(n1)C(C#N)c1nc2ccccc2s1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Serge Halazy, et al. Benzazole derivatives and their use as JNK modulators. EP1110957A1.
molnova catalog
related products
-
c-JUN peptide
Peptide comprising residues 33 - 57 of the JNK binding (δ) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor cells.
-
BI-78D3
A small molecule JIP1 mimic that functions as substrate competitive inhibitor of JNK with IC50 of 500 nM.
-
AS601245
A potent and selective inhibitor of JNK with IC50s of 70/220/150 nM for JNK1/2/3 respectively.
