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JNJ-64619178
CAS No. 2086772-26-9
JNJ-64619178 ( —— )
Catalog No. M23934 CAS No. 2086772-26-9
JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 160 | In Stock |
|
| 10MG | 236 | In Stock |
|
| 25MG | 395 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameJNJ-64619178
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NoteResearch use only, not for human use.
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Brief DescriptionJNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM).
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DescriptionJNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer.
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorPRMT5
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Research Area——
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Indication——
Chemical Information
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CAS Number2086772-26-9
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Formula Weight483.4
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Molecular FormulaC22H23BrN6O2
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Purity>98% (HPLC)
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SolubilityDMSO: 120 mg/mL (248.26 mM; Need ultrasonic)
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SMILESNc1c(ccn2[C@H](C[C@H](CCc3ccc(cc(c(N)n4)Br)c4c3)[C@H]3O)[C@@H]3O)c2ncn1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tongfei Wu, et al. Abstract 4859: JNJ-64619178, a selective and pseudo-irreversible PRMT5 inhibitor with potent in vitro and in vivo activity, demonstrated in several lung cancer models.
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