JK-P3
CAS No. 942655-44-9
JK-P3 ( 3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide )
Catalog No. M17680 CAS No. 942655-44-9
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 50 | In Stock |
|
10MG | 88 | In Stock |
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25MG | 200 | In Stock |
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50MG | 357 | In Stock |
|
100MG | 530 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameJK-P3
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NoteResearch use only, not for human use.
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Brief DescriptionJK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays.
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DescriptionJK-P3 is novel inhibitor of VEGFR-2. JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50 = 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
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Synonyms3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide
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PathwayOthers
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TargetOther Targets
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RecptorVEGFR2
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Research Area——
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Indication——
Chemical Information
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CAS Number942655-44-9
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Formula Weight323.35
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Molecular FormulaC18H17N3O3
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Purity98%
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Solubility——
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SMILESCOc1c(cc(cc1)C(=O)Nc1n[nH]c(c1)c1ccccc1)OC
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Chemical Name3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Antony M. Latham, et al. Identification of Receptor Tyrosine Kinase Inhibitors Using Cell Surface Biotinylation and Affinity Isolation. VEGF Signaling pp 121-131
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