Cart
sales@molnova.com
JK-P3
CAS No. 942655-44-9
JK-P3 ( 3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide )
Catalog No. M17680 CAS No. 942655-44-9
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 50 | In Stock |
|
| 10MG | 88 | In Stock |
|
| 25MG | 200 | In Stock |
|
| 50MG | 357 | In Stock |
|
| 100MG | 530 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameJK-P3
-
NoteResearch use only, not for human use.
-
Brief DescriptionJK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays.
-
DescriptionJK-P3 is novel inhibitor of VEGFR-2. JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50 = 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
-
Synonyms3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide
-
PathwayOthers
-
TargetOther Targets
-
RecptorVEGFR2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number942655-44-9
-
Formula Weight323.35
-
Molecular FormulaC18H17N3O3
-
Purity98%
-
Solubility——
-
SMILESCOc1c(cc(cc1)C(=O)Nc1n[nH]c(c1)c1ccccc1)OC
-
Chemical Name3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Antony M. Latham, et al. Identification of Receptor Tyrosine Kinase Inhibitors Using Cell Surface Biotinylation and Affinity Isolation. VEGF Signaling pp 121-131
Cite as
Cite as
molnova catalog
related products
-
SIYRY
SIYRY is a Kb-restricted epitope peptide.
-
2(1H)-Quinoxalinone
2(1H)-Quinoxalinone is a natural product extracted from edible flowers such as Clitoria ternatea and Hibiscus rosa sinensis.
-
ELN318463 racemate
ELN 318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC50s of 12nM and 656 nM for PS1and PS2, respectively.
