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JG26
CAS No. 1464910-32-4
JG26( —— )
Catalog No. M34294 CAS No. 1464910-32-4
JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 126 | Get Quote |
|
| 5MG | 188 | Get Quote |
|
| 10MG | 282 | Get Quote |
|
| 25MG | 481 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameJG26
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NoteResearch use only, not for human use.
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Brief DescriptionJG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively.
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DescriptionJG26 is an ADAM17 inhibitor, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM for ADAM8, ADAM17, ADAM10 and MMP-12, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorImmunology/Inflammation related | MMP
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Research Area——
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Indication——
Chemical Information
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CAS Number1464910-32-4
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Formula Weight594.27
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Molecular FormulaC19H22Br2N4O6S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (168.27 mM; Ultrasonic )
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SMILESS(N[C@H](CCCNC(N)=O)C(NO)=O)(=O)(=O)C1=CC=C(OCC2=CC(Br)=CC(Br)=C2)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Doretta Cuffaro, et al. Discovery of Dimeric Arylsulfonamides as Potent ADAM8 Inhibitors. ACS Med Chem Lett. 2021 Oct 8;12(11):1787-1793.?
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