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JAK-IN-5
CAS No. 2096999-92-5
JAK-IN-5( —— )
Catalog No. M26263 CAS No. 2096999-92-5
JAK-IN-5 is a JAK inhibitor (Compound 283 from patent US20170121327A1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 371 | Get Quote |
|
| 10MG | 552 | Get Quote |
|
| 25MG | 879 | Get Quote |
|
| 50MG | 1188 | Get Quote |
|
| 100MG | 1602 | Get Quote |
|
| 500MG | 3204 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameJAK-IN-5
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NoteResearch use only, not for human use.
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Brief DescriptionJAK-IN-5 is a JAK inhibitor (Compound 283 from patent US20170121327A1).
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DescriptionJAK-IN-5 is a JAK inhibitor (Compound 283 from patent US20170121327A1).
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In Vitro——
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In VivoJAK-IN-5 (compound 1) (oral aspirate, 0.5 mg/mL, 50 μL ) inhibits STAT6 phosphorylation by 60% in IL-13-induced in lung tissue in a mouse model of pSTAT6 induction.JAK-IN-5 (compound 1) (oral aspirate, 0.1-1.0 mg/mL, 50 μL) inhibits 88% of BALF eosinophils in male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung.
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Synonyms——
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PathwayAngiogenesis
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TargetJAK
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2096999-92-5
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Formula Weight474.584
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Molecular FormulaC27H31FN6O
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Purity>98% (HPLC)
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Solubility——
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SMILESCCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C1CCN(C)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhao H, Liu Q et al. In vitro additive antitumor effects of dimethoxycurcumin and 5-fluorouracil in colon cancer cells. Cancer Med. 2017 Jul;6(7):1698-1706.
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