J8-C8

CAS No. 1150565-77-7

J8-C8 ( acyl-HSLs inhibitor J8-C8 )

Catalog No. M10530 CAS No. 1150565-77-7

J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    J8-C8
  • Note
    Research use only, not for human use.
  • Brief Description
    J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
  • Description
    J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production; inhibits C8-HSL synthesis in a dose-dependent manner; a new class of quorum sensing (QS)-inhibiting therapeutic agents.
  • Synonyms
    acyl-HSLs inhibitor J8-C8
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1150565-77-7
  • Formula Weight
    237.34
  • Molecular Formula
    C14H23NO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    N-(3-oxocyclohex-1-en-1-yl)octanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chung J, et al. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12089-94.
molnova catalog
related products
  • Elubiol

    Elubiol is a new broad-spectrum antifungal product of imidazole, which can inhibit the biosynthesis of fungal ergosterol and change the composition of other lipid compounds in the cell membrane. Elubiol is used for skin and hair care in subjects with oily skin or dandruff.

  • MONOCAPRYLIN

    Monocaprylin is a monoglyceride of caprylic acid with an excellent?antibacterial?activity. Monocaprylin inhibits a variety of foodborne pathogenic and spoilage microorganisms and has the potential for an alternative food preservative research.

  • Indolicidin

    Indolicidin is comprised of 13 amino acids, 5 of which are tryptophan residues, and the carboxylterminal arginine is carboxamidated. Indolicidin has the highest tryptophan content of any known protein.Indolicidin is comprised of 13 amino acids, 5 of which are tryptophan residues, and the carboxylterminal arginine is carboxamidated.