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Itraconazole

CAS No. 84625-61-6

Itraconazole ( R51211 )

Catalog No. M16144 CAS No. 84625-61-6

A triazole antifungal agent for fungal infections via inhibition of lanosterol 14α-demethylase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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200MG 69 In Stock
500MG 160 In Stock
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Biological Information

  • Product Name
    Itraconazole
  • Note
    Research use only, not for human use.
  • Brief Description
    A triazole antifungal agent for fungal infections via inhibition of lanosterol 14α-demethylase.
  • Description
    A triazole antifungal agent for fungal infections via inhibition of lanosterol 14α-demethylase; also has been shown to inhibit both the hedgehog signaling pathway and angiogenesis.Fungal Infection Approved
  • Synonyms
    R51211
  • Pathway
    Microbiology/Virology
  • Target
    Fungal
  • Recptor
    CYP3A4
  • Research Area
    Infection
  • Indication
    Fungal Infection

Chemical Information

  • CAS Number
    84625-61-6
  • Formula Weight
    705.63
  • Molecular Formula
    C35H38Cl2N8O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 7.3 mg/mL
  • SMILES
    O=C1N(C(CC)C)N=CN1C2=CC=C(N3CCN(C4=CC=C(OC[C@@H]5O[C@@](CN6N=CN=C6)(C7=CC=C(Cl)C=C7Cl)OC5)C=C4)CC3)C=C2
  • Chemical Name
    3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-, rel-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kim J, et al. Cancer Cell. 2010 Apr 13;17(4):388-99.
2. Aftab BT, et al. Cancer Res. 2011 Nov 1;71(21):6764-72.
3. Chong CR, et al. ACS Chem Biol. 2007 Apr 24;2(4):263-70.
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