Isovalerylcarnitine

CAS No. 31023-24-2

Isovalerylcarnitine( —— )

Catalog No. M33605 CAS No. 31023-24-2

Isovalerylcarnitine (3-methylbutyrylcarnitine) is a small molecule compound produced by the catabolism of L-leucine and the accumulation of isovaleric acid.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Isovalerylcarnitine
  • Note
    Research use only, not for human use.
  • Brief Description
    Isovalerylcarnitine (3-methylbutyrylcarnitine) is a small molecule compound produced by the catabolism of L-leucine and the accumulation of isovaleric acid.
  • Description
    Isovalerylcarnitine is a product of the catabolism of L-leucine. Isovalerylcarnitine is also a selective and reversible calpain activator that induces apoptosis.
  • In Vitro
    Isovalerylcarnitine produces an early and marked increase in phagocytosis and also in cell killing, as well as reduces proliferation, in U937 leukemic cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Cysteine Protease
  • Recptor
    Cysteine Protease | Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    31023-24-2
  • Formula Weight
    245.32
  • Molecular Formula
    C12H23NO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (407.63 mM; Ultrasonic)DMSO : 50 mg/mL (203.82 mM; Ultrasonic )
  • SMILES
    CC(C)CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pontremoli S, et al. Isovalerylcarnitine is a specific activator of calpain of human neutrophils. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1189-95.?
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