Isovalerylcarnitine( —— )

Catalog No. M33605 CAS No. 31023-24-2

Isovalerylcarnitine (3-methylbutyrylcarnitine) is a small molecule compound produced by the catabolism of L-leucine and the accumulation of isovaleric acid.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Isovalerylcarnitine
Note

Research use only, not for human use.
Brief Description

Isovalerylcarnitine (3-methylbutyrylcarnitine) is a small molecule compound produced by the catabolism of L-leucine and the accumulation of isovaleric acid.
Description

Isovalerylcarnitine is a product of the catabolism of L-leucine. Isovalerylcarnitine is also a selective and reversible calpain activator that induces apoptosis.
In Vitro

Isovalerylcarnitine produces an early and marked increase in phagocytosis and also in cell killing, as well as reduces proliferation, in U937 leukemic cells.
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Cysteine Protease
Recptor

Cysteine Protease | Apoptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

31023-24-2
Formula Weight

245.32
Molecular Formula

C12H23NO4
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : 100 mg/mL (407.63 mM; Ultrasonic)DMSO : 50 mg/mL (203.82 mM; Ultrasonic )
SMILES

CC(C)CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pontremoli S, et al. Isovalerylcarnitine is a specific activator of calpain of human neutrophils. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1189-95.?

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