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Isofraxidin

CAS No. 486-21-5

Isofraxidin( Isofraxidin | Phytodolor )

Catalog No. M18627 CAS No. 486-21-5

Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 43 In Stock
10MG 74 In Stock
25MG 151 In Stock
50MG 227 In Stock
100MG 340 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Isofraxidin
  • Note
    Research use only, not for human use.
  • Brief Description
    Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.
  • Description
    Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Isofraxidin | Phytodolor
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    p38|ERK
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    486-21-5
  • Formula Weight
    222.19
  • Molecular Formula
    C11H10O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1125.16 mM)
  • SMILES
    COC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O
  • Chemical Name
    7-Hydroxy-6,8-dimethoxychromen-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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