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Isofraxidin

CAS No. 486-21-5

Isofraxidin ( Isofraxidin; Phytodolor )

Catalog No. M18627 CAS No. 486-21-5

Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.

Purity : 98%

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	43	In Stock
10MG	74	In Stock
25MG	151	In Stock
50MG	227	In Stock
100MG	340	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Isofraxidin
Note

Research use only, not for human use.
Brief Description

Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.
Description

Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
Synonyms

Isofraxidin; Phytodolor
Pathway

Others
Target

Other Targets
Recptor

p38;ERK
Research Area

Others-Field
Indication

——

Chemical Information

CAS Number

486-21-5
Formula Weight

222.19
Molecular Formula

C11H10O5
Purity

98%
Solubility

——
SMILES

COC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O
Chemical Name

7-Hydroxy-6,8-dimethoxychromen-2-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

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