Isofraxidin

CAS No. 486-21-5

Isofraxidin( Isofraxidin | Phytodolor )

Catalog No. M18627 CAS No. 486-21-5

Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 43 In Stock
10MG 74 In Stock
25MG 151 In Stock
50MG 227 In Stock
100MG 340 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Isofraxidin
  • Note
    Research use only, not for human use.
  • Brief Description
    Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.
  • Description
    Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Isofraxidin | Phytodolor
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    p38|ERK
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    486-21-5
  • Formula Weight
    222.19
  • Molecular Formula
    C11H10O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1125.16 mM)
  • SMILES
    COC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O
  • Chemical Name
    7-Hydroxy-6,8-dimethoxychromen-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • KL201

    KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues.

  • 6-Fluorotryptamine h...

    6-Fluorotryptamine hydrochloride is a compound used as a molecular building block.

  • TCS 1105

    TCS 1105 is a GABAA benzodiazepine receptor (BZR) ligand. TCS 1105 blocks Sema3A induced axonal growth cones collapse. TCS 1105 reduces anxiety-like behavior and enhances offensive behavior and social dominance in mice.