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Isodeoxyelephantopin

CAS No. 38927-54-7

Isodeoxyelephantopin( —— )

Catalog No. M29060 CAS No. 38927-54-7

Isodeoxyelephantopin can inhibit the growth of various tumor cells.

Purity : >98% (HPLC)

COA

Datasheet

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Biological Information

Product Name

Isodeoxyelephantopin
Note

Research use only, not for human use.
Brief Description

Isodeoxyelephantopin can inhibit the growth of various tumor cells.
Description

Isodeoxyelephantopin can inhibit the growth of various tumor cells.(In Vitro):Isodeoxyelephantopin inhibits the growth of A549 and T47D cells in a dose-dependent and time-dependent manner with IC50 values of 10.46 and 1.3 μg/mL, respectively. Heterodeoxyelephantin showed no significant toxicity to normal lymphocytes. Heterodeoxyelephinin-induced cell death is associated with activated caspase-3 expression, followed by cell cycle stagnation in G2/M phase .
In Vitro

Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop.
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

NF-κB
Recptor

NF-κB
Research Area

——
Indication

——

Chemical Information

CAS Number

38927-54-7
Formula Weight

344.363
Molecular Formula

C19H20O6
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(=C)C(=O)O[C@H]1CC2=C[C@H](C\C(C)=C/[C@H]3OC(=O)C(=C)[C@H]13)OC2=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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