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Isodeoxyelephantopin

CAS No. 38927-54-7

Isodeoxyelephantopin( —— )

Catalog No. M29060 CAS No. 38927-54-7

Isodeoxyelephantopin can inhibit the growth of various tumor cells.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Isodeoxyelephantopin
  • Note
    Research use only, not for human use.
  • Brief Description
    Isodeoxyelephantopin can inhibit the growth of various tumor cells.
  • Description
    Isodeoxyelephantopin can inhibit the growth of various tumor cells.(In Vitro):Isodeoxyelephantopin inhibits the growth of A549 and T47D cells in a dose-dependent and time-dependent manner with IC50 values of 10.46 and 1.3 μg/mL, respectively. Heterodeoxyelephantin showed no significant toxicity to normal lymphocytes. Heterodeoxyelephinin-induced cell death is associated with activated caspase-3 expression, followed by cell cycle stagnation in G2/M phase .
  • In Vitro
    Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    38927-54-7
  • Formula Weight
    344.363
  • Molecular Formula
    C19H20O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(=C)C(=O)O[C@H]1CC2=C[C@H](C\C(C)=C/[C@H]3OC(=O)C(=C)[C@H]13)OC2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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