Ingenol ( Ingenol )

Catalog No. M18390 CAS No. 30220-46-3

COA

Datasheet

HNMR

HPLC

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Product Name

Ingenol
Note

Research use only, not for human use.
Brief Description

Ingenol mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV.
Description

Ingenol is a diterpenoid related to phorbol, derived from the milkweed plant E. peplus. Most ingenol esters are tumor-promoting. However, ingenol mebutate possesses anti-tumor activity when used topically for actinic keratosis.
Synonyms

Ingenol
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Cancer
Indication

——

CAS Number

30220-46-3
Formula Weight

348.43
Molecular Formula

C20H28O5
Purity

98%
Solubility

DMSO : 100 mg/mL 287.00 mM;
SMILES

CC1CC2C(C2(C)C)C3C=C(C(C4(C1(C3=O)C=C(C4O)C)O)O)CO
Chemical Name

(1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one