Cart
sales@molnova.com
Indobufen
CAS No. 63610-08-2
Indobufen ( Ibustrin )
Catalog No. M26717 CAS No. 63610-08-2
Indobufen is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 36 | In Stock |
|
| 10MG | 51 | In Stock |
|
| 25MG | 85 | In Stock |
|
| 50MG | 124 | In Stock |
|
| 100MG | 178 | In Stock |
|
| 200MG | 267 | In Stock |
|
| 500MG | 461 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameIndobufen
-
NoteResearch use only, not for human use.
-
Brief DescriptionIndobufen is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
-
DescriptionIndobufen is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.(In Vitro):Indobufen suppresses TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen causes the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered. Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels.
-
SynonymsIbustrin
-
PathwayChromatin/Epigenetic
-
TargetCOX
-
RecptorRSV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number63610-08-2
-
Formula Weight295.3
-
Molecular FormulaC18H17NO3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCC(C(O)=O)c1ccc(cc1)N1Cc2ccccc2C1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Lundin A, et al. Two novel fusion inhibitors of human respiratory syncytial virus. Antiviral Res. 2010 Dec;88(3):317-24.
molnova catalog
related products
-
4-Aminoantipyrine
4-Aminoantipyrine is a reagent for glucose determination in the presence of peroxidase and phenol.
-
Tilmacoxib
Tilmacoxib (JTE-522) is a potent, selective inhibitor of cyclooxygenase-2 (COX-2) that inhibits human recombinant COX-2 with IC50 of 85 nM.
-
Ruscogenin
Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner.
