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Indazole-Cl
CAS No. 848142-62-1
Indazole-Cl( —— )
Catalog No. M34085 CAS No. 848142-62-1
Indazole-Cl is a selective ER? agonist and a selective estrogen receptor modifier (SERM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 178 | Get Quote |
|
| 5MG | 255 | Get Quote |
|
| 10MG | 375 | Get Quote |
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| 25MG | 545 | Get Quote |
|
| 50MG | 762 | Get Quote |
|
| 100MG | 1017 | Get Quote |
|
| 200MG | 1377 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIndazole-Cl
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NoteResearch use only, not for human use.
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Brief DescriptionIndazole-Cl is a selective ER? agonist and a selective estrogen receptor modifier (SERM).
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DescriptionIndazole-Cl (Ind-Cl) is an Estrogen receptor (ER)-β-specific agonist with inflammatory effect. Indazole-Cl inhibits cyclooxygenase-2 exression reduction induced by hypoxia. And Indazole-Cl inhibits ROS production. Indazole-Cl also inhibits cell migration and invasion by hypoxia increased by hypoxia. Indazole-Cl is potent inhibitor of hypoxia-induced in?ammation in vascular smooth muscle cells (VSMCs).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptorEstrogen/progestogen Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number848142-62-1
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Formula Weight260.68
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Molecular FormulaC13H9ClN2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESClC=1N(N=C2C1C=C(O)C=C2)C3=CC=C(O)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Park C, et al. Indazole-Cl inhibits hypoxia-induced cyclooxygenase-2 expression in vascular smooth muscle cells. J Mol Endocrinol. 2019 Jul 1;63(1):27-38. ?
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