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Inaxaplin

CAS No. 2446816-88-0

Inaxaplin( VX-147 )

Catalog No. M28276 CAS No. 2446816-88-0

Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.

Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Inaxaplin
  • Note
    Research use only, not for human use.
  • Brief Description
    Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.
  • Description
    Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.(In Vitro):Inaxaplin is an apolipoprotein L1 function inhibitor.
  • In Vitro
  • In Vivo
  • Synonyms
    VX-147
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    14-3-3 protein-protein interaction
  • Research Area
  • Indication

Chemical Information

  • CAS Number
    2446816-88-0
  • Formula Weight
    417.38
  • Molecular Formula
    C21H18F3N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (119.79 mM)
  • SMILES
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mancini M, et al. A new nonpeptidic inhibitor of 14-3-3 induces apoptotic cell death in chronic myeloid leukemia sensitive or resistant to imatinib. J Pharmacol Exp Ther. 2011 Mar;336(3):596-604.
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