Inaxaplin( VX-147 )

Catalog No. M28276 CAS No. 2446816-88-0

Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	881	Get Quote
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Biological Information

Product Name

Inaxaplin
Note

Research use only, not for human use.
Brief Description

Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.
Description

Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.(In Vitro):Inaxaplin is an apolipoprotein L1 function inhibitor.
In Vitro

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In Vivo

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Synonyms

VX-147
Pathway

Others
Target

Other Targets
Recptor

14-3-3 protein-protein interaction
Research Area

——
Indication

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Chemical Information

CAS Number

2446816-88-0
Formula Weight

417.38
Molecular Formula

C21H18F3N3O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (119.79 mM)
SMILES

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Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Mancini M, et al. A new nonpeptidic inhibitor of 14-3-3 induces apoptotic cell death in chronic myeloid leukemia sensitive or resistant to imatinib. J Pharmacol Exp Ther. 2011 Mar;336(3):596-604.

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