Cart
sales@molnova.com
Imiquimod hydrochloride
CAS No. 99011-78-6
Imiquimod hydrochloride( —— )
Catalog No. M33785 CAS No. 99011-78-6
Imiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 30 | In Stock |
|
| 100MG | 41 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameImiquimod hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionImiquimod hydrochloride (R 837 hydrochloride), a selective toll-like receptor 7 (TLR7) agonist, functions as an immune response modifier with in vivo antiviral and antitumor properties, and is utilized in researching external genital and perianal warts, cancer, and COVID-19 .
-
DescriptionImiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetTLR
-
RecptorTLR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number99011-78-6
-
Formula Weight276.77
-
Molecular FormulaC14H17ClN4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?Methanol : 24 mg/mL (86.72 mM; Ultrasonic)DMSO : 8 mg/mL (28.91 mM; Ultrasonic (<50°C); )H2O : 4.8 mg/mL (17.34 mM; Ultrasonic)Ethanol : 3.85 mg/mL (13.91 mM; Ultrasonic)
-
SMILESCl.CC(C)Cn1cnc2c(N)nc3ccccc3c12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Athina Angelopoulou, et al. Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19. Environ Res. 2020 Sep; 188: 109858.?
molnova catalog
related products
-
Semapimod
Semapimod (CNI 1493;AXD-455) is a tetravalent guanylhydrazone that acts as a selective inhibitor of cytokine-inducible arginine transport and NO production, inhibits TLR4 signaling (IC50=0.3 uM) .
-
RS09 2TFA 1449566-36...
RS09 2TFA is a TLR4 agonist.?Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro.??It acts as an adjuvant in vivo and enhances X-15 specific antibody serum concentrations.
-
CPG-52364
CPG-52364 (CPG52364) is an orally available, small molecule TLR7/8/9 antagonist for the treatment of systemic lupus erythematosus and other autoimmune disorders.
