Iloperidone
CAS No. 133454-47-4
Iloperidone ( HP-873 )
Catalog No. M11335 CAS No. 133454-47-4
An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 30 | In Stock |
|
10MG | 45 | In Stock |
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25MG | 86 | In Stock |
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50MG | 149 | In Stock |
|
100MG | 221 | In Stock |
|
200MG | 327 | In Stock |
|
500MG | 529 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameIloperidone
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NoteResearch use only, not for human use.
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Brief DescriptionAn atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM).
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DescriptionAn atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors; is used for the treatment of schizophrenia.Schizophrenia Approved
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SynonymsHP-873
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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RecptorDopamine;α-adrenergicreceptor
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Research AreaNeurological Disease
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IndicationSchizophrenia
Chemical Information
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CAS Number133454-47-4
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Formula Weight426.48
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Molecular FormulaC24H27FN2O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC(C1=CC=C(OCCCN2CCC(C3=NOC4=CC(F)=CC=C34)CC2)C(OC)=C1)=O
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Chemical NameEthanone, 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Barr AM, et al. Neuropharmacology. 2006 Sep;51(3):457-65.
2. Szewczak MR, et al. J Pharmacol Exp Ther. 1995 Sep;274(3):1404-13.
3. Sainati SM, et al. J Clin Pharmacol. 1995 Jul;35(7):713-20.
2. Szewczak MR, et al. J Pharmacol Exp Ther. 1995 Sep;274(3):1404-13.
3. Sainati SM, et al. J Clin Pharmacol. 1995 Jul;35(7):713-20.
molnova catalog
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