Iloperidone

CAS No. 133454-47-4

Iloperidone ( HP-873 )

Catalog No. M11335 CAS No. 133454-47-4

An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 30 In Stock
10MG 45 In Stock
25MG 86 In Stock
50MG 149 In Stock
100MG 221 In Stock
200MG 327 In Stock
500MG 529 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Iloperidone
  • Note
    Research use only, not for human use.
  • Brief Description
    An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM).
  • Description
    An atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors; is used for the treatment of schizophrenia.Schizophrenia Approved
  • Synonyms
    HP-873
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    Dopamine;α-adrenergicreceptor
  • Research Area
    Neurological Disease
  • Indication
    Schizophrenia

Chemical Information

  • CAS Number
    133454-47-4
  • Formula Weight
    426.48
  • Molecular Formula
    C24H27FN2O4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC(C1=CC=C(OCCCN2CCC(C3=NOC4=CC(F)=CC=C34)CC2)C(OC)=C1)=O
  • Chemical Name
    Ethanone, 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Barr AM, et al. Neuropharmacology. 2006 Sep;51(3):457-65.
2. Szewczak MR, et al. J Pharmacol Exp Ther. 1995 Sep;274(3):1404-13.
3. Sainati SM, et al. J Clin Pharmacol. 1995 Jul;35(7):713-20.
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