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Iclaprim

CAS No. 192314-93-5

Iclaprim( AR-100 )

Catalog No. M23874 CAS No. 192314-93-5

Iclaprim is a novel specific bacterial Dihydrofolate inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Iclaprim
  • Note
    Research use only, not for human use.
  • Brief Description
    Iclaprim is a novel specific bacterial Dihydrofolate inhibitor.
  • Description
    Iclaprim is a novel specific bacterial Dihydrofolate inhibitor. It can inhibit the growth of S. aureus (MIC90: 0.06 μg/mL).(In Vitro):Iclaprim inhibits the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
  • In Vitro
    Iclaprim inhibits the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
  • In Vivo
    ——
  • Synonyms
    AR-100
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial|Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    192314-93-5
  • Formula Weight
    354.4
  • Molecular Formula
    C19H22N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:28 mg/mL (79 mM; Need ultrasonic and warming)
  • SMILES
    COc1cc(Cc2c(N)nc(N)nc2)c(C=CC(C2CC2)O2)c2c1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Schneider P, et al. Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4217-21.
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