Ibudilast

CAS No. 50847-11-5

Ibudilast( AV 411 | KC-404 )

Catalog No. M14741 CAS No. 50847-11-5

Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 35 In Stock
25MG 43 In Stock
50MG 47 In Stock
100MG 70 In Stock
200MG 91 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Ibudilast
  • Note
    Research use only, not for human use.
  • Brief Description
    Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma.
  • Description
    Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma.
  • In Vitro
    Western Blot Analysis Cell Line:Microglia Concentration:1~100 μM Incubation Time:24 hours Result:Suppressed both IL-1β and IL-6 production at 100 μM, and significantly suppresses TNF-α production at 10 and 100 μM. ?
  • In Vivo
    ——
  • Synonyms
    AV 411 | KC-404
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    50847-11-5
  • Formula Weight
    230.51
  • Molecular Formula
    C14H18N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 28 mg/mL; 100 mM in Ethanol
  • SMILES
    CC(C)C(C1=C2C=CC=CN2N=C1C(C)C)=O
  • Chemical Name
    2-methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yamazaki T, et al. Eur J Pharmacol. 2010 Oct 29.
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