Ibrolipim ( NO-1886 )

Catalog No. M21132 CAS No. 133208-93-2

Ibrolipim attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.

Purity : >98% (HPLC)

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Biological Information

Product Name

Ibrolipim
Note

Research use only not for human use.
Brief Description

Ibrolipim attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.
Description

Ibrolipim attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.
Synonyms

NO-1886
Pathway

Others
Target

Other Targets
Recptor

Lipoprotein lipase (LPL)
Research Area

——
Indication

——

Chemical Information

CAS Number

133208-93-2
Formula Weight

451.25
Molecular Formula

Br1C19H20N2O4P1
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL (277.01 mM; Need ultrasonic)
SMILES

CCOP(=O)(Cc1ccc(C(=O)Nc2ccc(Br)cc2C#N)cc1)OCC
Chemical Name

Diethyl (4-((4-bromo-2-cyanophenyl)carbamoyl)benzyl)phosphonate

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Chen SG et al. Ibrolipim increases ABCA1/G1 expression by the LXRα signaling pathway in THP-1 macrophage-derived foam cells. Acta Pharmacol Sin. 2010 Oct;31(10):1343-9.

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