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Iberdomide

CAS No. 1323403-33-3

Iberdomide ( CC-220 )

Catalog No. M21067 CAS No. 1323403-33-3

Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Iberdomide
  • Note
    Research use only not for human use.
  • Brief Description
    Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
  • Description
    Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
  • Synonyms
    CC-220
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1323403-33-3
  • Formula Weight
    449.5
  • Molecular Formula
    C25H27N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:30 mg/mL (66.74 mM)
  • SMILES
    O=C1CCC(N2Cc3c(OCc4ccc(CN5CCOCC5)cc4)cccc3C2=O)C(=O)N1
  • Chemical Name
    (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-26-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Matyskiela M E Zhang W Man H W et al. A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos[J]. Journal of Medicinal Chemistry 2017:acs.jmedchem.6b01921.
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