Cart
sales@molnova.com
IWP-L6
CAS No. 1427782-89-5
IWP-L6 ( IWP-L6;PORCN Inhibitor III )
Catalog No. M17292 CAS No. 1427782-89-5
IWP-L6 is an extremely effective Porcn inhibitor (EC50: 0.5 nM).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 37 | In Stock |
|
| 10MG | 56 | In Stock |
|
| 25MG | 104 | In Stock |
|
| 50MG | 178 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameIWP-L6
-
NoteResearch use only, not for human use.
-
Brief DescriptionIWP-L6 is an extremely effective Porcn inhibitor (EC50: 0.5 nM).
-
DescriptionIWP-L6, also known as PORCN Inhibitor III and Wnt Pathway Inhibitor XIX, is a potent inhibitor of PORCN (EC50 = 0.5 nM). Porcupine is a member of the membrane-bound O-acyltransferase family of proteins. It catalyzes the palmitoylation of Wnt proteins, a process required for their secretion and activity.
-
SynonymsIWP-L6;PORCN Inhibitor III
-
PathwayOthers
-
TargetOther Targets
-
RecptorPorcn
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1427782-89-5
-
Formula Weight472.58
-
Molecular FormulaC25H20N4O2S2
-
Purity98%
-
SolubilityDMSO : 1.43 mg/mL 3.03 mM;
-
SMILESO=C(CSc1nc2c(SCC2)c(=O)n1c1ccccc1)Nc1ncc(cc1)c1ccccc1
-
Chemical NameN-(5-phenyl-2-pyridinyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang X, et al. J Med Chem. 2013, 56(6), 2700-2704.
molnova catalog
related products
-
Theaflavin-3'-Gallat...
Theaflavin-3'-gallate, act as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than normal fibroblasts.
-
MTOB
MTOB is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, leading to cancer stem cell (CSC) growth and self-renewal.
-
Dropropizine
Dropropizine is a racemic non-opiate antitussive agent, it is used as a cough suppressant.
