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Home - Products - Cell Cycle/DNA Damage - HDAC - ITF3756

ITF3756

CAS No. 2247608-27-9

ITF3756( —— )

Catalog No. M36305 CAS No. 2247608-27-9

ITF3756 is a selective HDAC6 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 97 Get Quote
5MG 148 Get Quote
10MG 227 Get Quote
25MG 394 Get Quote
50MG 573 Get Quote
100MG 790 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    ITF3756
  • Note
    Research use only, not for human use.
  • Brief Description
    ITF3756 is a selective HDAC6 inhibitor.
  • Description
    ITF 3756 is a potent and selective HDAC6 inhibitor. ITF 3756 reduces in vitro the expression of PD-L1 on human monocytes and on CD8 T cells, and shows anti-tumor activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2247608-27-9
  • Formula Weight
    301.32
  • Molecular Formula
    C13H11N5O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (414.84 mM; Ultrasonic )
  • SMILES
    C(N1C(=NN=N1)C2=CC=CS2)C3=CC=C(C(NO)=O)C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gianluca Fossati, et al. Abstract 1358: The selective HDAC6 inhibitor ITF3756 stimulates an antitumor immune response and leads to tumor regression in combination with anti CTLA-4 antibody in a colon carcinoma murine model. Cancer Res (2022) 82 (12_Supplement): 1358.
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