Cart
sales@molnova.com
ISRIB
CAS No. 548470-11-7
ISRIB( —— )
Catalog No. M14973 CAS No. 548470-11-7
ISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 43 | In Stock |
|
| 10MG | 70 | In Stock |
|
| 25MG | 141 | In Stock |
|
| 50MG | 239 | In Stock |
|
| 100MG | 350 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameISRIB
-
NoteResearch use only, not for human use.
-
Brief DescriptionISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.
-
DescriptionISRIB is a potent and selective PERK inhibitor with IC50 of 5 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMAPK/ERK Signaling
-
TargetERK
-
RecptorPERK
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number548470-11-7
-
Formula Weight451.34
-
Molecular FormulaC22H24Cl2N2O4
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM
-
SMILESClC1=CC=C(OCC(=O)NC2CCC(CC2)NC(=O)COC2=CC=C(Cl)C=C2)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sidrauski C, et al. Elife. 2013, 2, e00498.
molnova catalog
related products
-
MK-8353
MK-8353 (SCH-900353) is a?highly potent, orally bioavailable, dual-specificity ERK1/2 inhibitor with IC50 of 23.0/8.8 nM, respectively.
-
AZD0364
AZD0364 (AZD-0364) is a potent, selective, orally active ERK1/2 inhibitor for treatment of NSCLC.
-
VX-11e
A potent, selective, and orally bioavailable inhibitor of ERK2 with Ki of <2 nM.
