IRAK4-IN-4

CAS No. 1850276-58-2

IRAK4-IN-4 ( —— )

Catalog No. M22690 CAS No. 1850276-58-2

IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 169 In Stock
5MG 262 In Stock
10MG 411 In Stock
25MG 678 In Stock
50MG 954 In Stock
100MG 1287 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    IRAK4-IN-4
  • Note
    Research use only, not for human use.
  • Brief Description
    IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
  • Description
    IRAK4-IN-4 inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    IRAK4;cGAS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1850276-58-2
  • Formula Weight
    340.37
  • Molecular Formula
    C22H16N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:24 mg/mL(70.51 mM)
  • SMILES
    Cc1ccn2c(C(=O)C(=O)c3ccccc3)c(nc2c1)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.One class has the naphthalene second dione compounds and its derivative of protease modification activities. CN107163044A.
molnova catalog
related products
  • DSP-0565

    DSP-0565 exhibits anti-convulsant activity and good safety margin in various models including scPTZ, 6 Hz, MES, and amygdala kindling.

  • BC-1382

    BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS)- and Pseudomonas aeruginosa-induced lung inflammation.?

  • GK921

    GK921 is a transglutaminase 2 (TGase) inhibitor.