IQDMA

CAS No. 401463-02-3

IQDMA( C524250 | IQDMA cpd | IQDMA )

Catalog No. M14373 CAS No. 401463-02-3

A cell-permeable, small molecule inhibitor of the transcription factor STAT5.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    IQDMA
  • Note
    Research use only, not for human use.
  • Brief Description
    A cell-permeable, small molecule inhibitor of the transcription factor STAT5.
  • Description
    A cell-permeable, small molecule inhibitor of the transcription factor STAT5 that exhibits anticancer activity and inhibits the growth of A549, HL-60 and K562 cells with IC50 of 8, 5 and 8 uM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    C524250 | IQDMA cpd | IQDMA
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    401463-02-3
  • Formula Weight
    304.397
  • Molecular Formula
    C19H20N4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN(C)CCNC1=NC2=CC=CC=C2C3=C1C4=C(N3)C=CC=C4
  • Chemical Name
    N'-(11H-indolo[3,2-c]quinolin-6-yl)-N,N-dimethylethane-1,2-diamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hu XW, et al. Cell Biol Toxicol. 2006 Nov;22(6):417-27. 2. Chien CM, et al. Chem Biol Interact. 2008 Oct 22;176(1):40-7. 3. Hodge LS, et al. Blood. 2014 Feb 13;123(7):1055-8.
molnova catalog
related products
  • Hydrazinocurcumin

    Hydrazinocurcumin is a synthetic curcumin derivative that inhibits the proliferation of bovine aortic endothelial cells (BAECs) with IC50 of 520 nM without cytotoxicity.

  • Niclosamide

    Niclosamide(BAY2353) is used for the treatment of most tapeworm infections by inhibiting DNA replication.

  • MMPP

    MMPP is a novel VEGFR2 inhibitor with anti-inflammatory and potential anticancer activity, inhibits STAT3, inhibits angiogenesis via VEGFR2/AKT/ERK/NF-kappaB pathway, and can be used to alleviate myocardial injury.