Cart
sales@molnova.com
IQDMA
CAS No. 401463-02-3
IQDMA ( C524250; IQDMA cpd; IQDMA )
Catalog No. M14373 CAS No. 401463-02-3
A cell-permeable, small molecule inhibitor of the transcription factor STAT5.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameIQDMA
-
NoteResearch use only, not for human use.
-
Brief DescriptionA cell-permeable, small molecule inhibitor of the transcription factor STAT5.
-
DescriptionA cell-permeable, small molecule inhibitor of the transcription factor STAT5 that exhibits anticancer activity and inhibits the growth of A549, HL-60 and K562 cells with IC50 of 8, 5 and 8 uM, respectively.
-
SynonymsC524250; IQDMA cpd; IQDMA
-
PathwayJAK/STAT Signaling
-
TargetSTAT
-
RecptorSTAT
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number401463-02-3
-
Formula Weight304.40
-
Molecular FormulaC19H20N4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN(C)CCNC1=NC2=CC=CC=C2C3=C1C4=C(N3)C=CC=C4
-
Chemical NameN'-(11H-indolo[3,2-c]quinolin-6-yl)-N,N-dimethylethane-1,2-diamine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hu XW, et al. Cell Biol Toxicol. 2006 Nov;22(6):417-27.
2. Chien CM, et al. Chem Biol Interact. 2008 Oct 22;176(1):40-7.
3. Hodge LS, et al. Blood. 2014 Feb 13;123(7):1055-8.
2. Chien CM, et al. Chem Biol Interact. 2008 Oct 22;176(1):40-7.
3. Hodge LS, et al. Blood. 2014 Feb 13;123(7):1055-8.
molnova catalog
related products
-
Pomstafib-1
The cell-permeable, pivaloyloxymethylester of Stafib-1, which is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 44 nM.
-
Noricaritin
——
-
NSC 370284
NSC 370284 is a small molecule that directly binds to and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.
