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IP7e
CAS No. 500164-74-9
IP7e ( IP 7e;IP-7e;isoxazolo-pyridinone 7e )
Catalog No. M27887 CAS No. 500164-74-9
IP7e is a Nurr1 activator with an EC50 value of 3.9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 356 | Get Quote |
|
| 10MG | 530 | Get Quote |
|
| 25MG | 851 | Get Quote |
|
| 50MG | 1152 | Get Quote |
|
| 100MG | 1557 | Get Quote |
|
| 500MG | 3114 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameIP7e
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NoteResearch use only, not for human use.
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Brief DescriptionIP7e is a Nurr1 activator with an EC50 value of 3.9 nM.
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DescriptionIP7e is a Nurr1 activator with an EC50 value of 3.9 nM.(In Vivo):IP7e(10 mg/kg) attenuates inflammation and neurodegeneration in spinal cords of EAE mice by an NF-kB pathway-dependent process. IP7e preventive treatment reduces the incidence and the severity of an MS murine model, i.e. experimental autoimmune encephalomyelitis (EAE).
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SynonymsIP 7e;IP-7e;isoxazolo-pyridinone 7e
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PathwayOthers
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TargetOther Targets
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RecptorACMSD
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Research Area——
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Indication——
Chemical Information
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CAS Number500164-74-9
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Formula Weight390.4
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Molecular FormulaC23H22N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCOCCOCc1ccc(cc1)-c1cc2onc(-c3ccccc3)c2c(=O)n1C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pellicciari R, et al. α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis. J Med Chem. 2018 Feb 8;61(3):745-759.
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