Cart
sales@molnova.com
INI-43
CAS No. 881046-01-1
INI-43( INI 43 | INI43 | INI-43 )
Catalog No. M27884 CAS No. 881046-01-1
INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NF.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | Get Quote |
|
| 10MG | 129 | Get Quote |
|
| 25MG | 260 | Get Quote |
|
| 50MG | 410 | Get Quote |
|
| 100MG | 605 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameINI-43
-
NoteResearch use only, not for human use.
-
Brief DescriptionINI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NF.
-
DescriptionINI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NF.
-
In Vitro——
-
In Vivo——
-
SynonymsINI 43 | INI43 | INI-43
-
PathwayOthers
-
TargetOther Targets
-
RecptorPLD1|PLD2|Dopamine Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number881046-01-1
-
Formula Weight385.475
-
Molecular FormulaC22H23N7
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 10 mg/mL (25.94 mM)
-
SMILESCN(C)CCCn1c(N)c(-c2nc3ccccc3[nH]2)c2nc3ccccc3nc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Skafi N, et al. Phospholipase D: A new mediator during high phosphate-induced vascular calcification associated with chronic kidney disease. J Cell Physiol. 2019 Apr;234(4):4825-4839.
molnova catalog
related products
-
Temozolomide Acid
Temozolomide Acid is a metabolite of temozolomide (TMZ). Temozolomide processes anticancer activity in vitro. Temozolomide (TMZ) is an oral alkylating agent used to treat glioblastoma multiforme (GBM) and astrocytomas.
-
Sodium Thiocyanate
Sodium Thiocyanate one of the main sources of the thiocyanate anion is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.
-
Dimethylamine hydroc...
Dimethylamine (DMA) is abundantly present in human urine. Main sources of urinary DMA have been reported to include trimethylamine N-oxide a common food component and asymmetric dimethylarginine (ADMA) an endogenous inhibitor of nitric oxide (NO) synthesis.
