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IMP-1088

CAS No. 2059148-82-0

IMP-1088 ( —— )

Catalog No. M28622 CAS No. 2059148-82-0

IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 219 Get Quote
5MG 327 Get Quote
10MG 489 Get Quote
25MG 789 Get Quote
50MG 1062 Get Quote
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Biological Information

  • Product Name
    IMP-1088
  • Note
    Research use only, not for human use.
  • Brief Description
    IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.
  • Description
    IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.(In Vitro):IMP-1088 (1-1000 nM) blocks production of infectious virus and inhibits single cycle replication in primary human bronchial epithelial cells (hBEC) infected with rhinovirus RV-A1 (MOI 5) for 7 h. IMP-1088 significantly inhibits production of infectious virus even when added up to 3 hours post-infection.IMP-1088 (500 nM) inhibits production of infectious rhinovirus particles by blocking virus assembly in HeLa cells infected with rhinovirus RV-A16 (MOI 20) for 6 h.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    D4 Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2059148-82-0
  • Formula Weight
    453.5
  • Molecular Formula
    C25H29F2N5O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1c(CCOc(c(-c(cc2)cc3c2n(C)nc3CN(C)C)ccc2F)c2F)c(C)nn1C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Belliotti TR, et al. Isoindolinone enantiomers having affinity for the dopamine D4 receptor. Bioorg Med Chem Lett. 1998 Jun 16;8(12):1499-502.
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