IDX-17119

CAS No. 1987906-92-2

IDX-17119( IDX17119 )

Catalog No. M13106 CAS No. 1987906-92-2

IDX-17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assay.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    IDX-17119
  • Note
    Research use only, not for human use.
  • Brief Description
    IDX-17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assay.
  • Description
    IDX-17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assay; shows activity against broad genotype profile: IC50= 0.0099 uM, 0.2538 uM, 0.1809 uM and 0.0257 uM on genotypes 1b, 2a, 3a and 4a, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    IDX17119
  • Pathway
    Microbiology/Virology
  • Target
    HCV
  • Recptor
    HCV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1987906-92-2
  • Formula Weight
    531.513
  • Molecular Formula
    C26H26N7O4P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=CC(=C(C=C1)P(=O)(NC2=NN(C=C2C(=O)O)C3=CC=C(C=C3)C4=NN5C(=CC(=NC5=C4)C)N)OC)C
  • Chemical Name
    1-(4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-2-yl)phenyl)-3-(((2,4-dimethylphenyl)(methoxy)phosphoryl)amino)-1H-pyrazole-4-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pierra Rouvière C, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4536-41.
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