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IDE1

CAS No. 1160927-48-9

IDE1 ( IDE1; IDE-1; IDE 1 )

Catalog No. M17158 CAS No. 1160927-48-9

IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells.

Purity : 98%

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10MG	135	In Stock
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Biological Information

Product Name

IDE1
Note

Research use only, not for human use.
Brief Description

IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells.
Description

IDE1 is a potent cell-permeable definitive endoderm formation inducer (EC50 = 125 nM, ESC) similar to IDE 2 (ab145223). IDE1 induces Sox17 expression. It also activates TGF-β signaling and downstream Smad2 phosphorylation. IDE1 upregulates Nodal expression.
Synonyms

IDE1; IDE-1; IDE 1
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Inflammation/Immunology
Indication

——

Chemical Information

CAS Number

1160927-48-9
Formula Weight

306.3
Molecular Formula

C15H18N2O5
Purity

98%
Solubility

DMSO : ≥ 30 mg/mL 97.94 mM
SMILES

c1ccc(c(c1)/C=N/NC(=O)CCCCCC(=O)O)C(=O)O
Chemical Name

7-[2-(2-Carboxybenzylidene)hydrazinyl]-7-oxoheptanoic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hoveizi E, et al. J Biomed Mater Res A. 2014 Nov;102(11):4027-36.

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