ICCB280 ( —— )

Catalog No. M23912 CAS No. 2041072-41-5

ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome resistance to other current therapies for AML with an unfavorable prognosis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	97	In Stock
5MG	160	In Stock
10MG	290	In Stock
25MG	470	In Stock
50MG	683	In Stock
100MG	954	In Stock
500MG	1917	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ICCB280
Note

Research use only, not for human use.
Brief Description

ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome resistance to other current therapies for AML with an unfavorable prognosis.
Description

ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome resistance to other current therapies for AML with an unfavorable prognosis.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

C/EBPα
Research Area

——
Indication

——

Chemical Information

CAS Number

2041072-41-5
Formula Weight

386.4
Molecular Formula

C23H18N2O4
Purity

>98% (HPLC)
Solubility

DMSO:85mg/mL (219.98mM)
SMILES

O=C1N(C2=CC=CC=C2OC)C(/C=C/C3=CC=C(O)C(O)=C3)=NC4=C1C=CC=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Radomska HS, Jernigan F, Nakayama S, et al. A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation. J Biomol Screen. 2015;20(9):1150-1159. doi:10.1177/1087057115592220

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