I-2906 ( I 2906;I2906 )

Catalog No. M14114 CAS No. 331963-29-2

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Product Name

I-2906
Note

Research use only, not for human use.
Brief Description

A novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity.
Description

A novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity; shows good activity against M. tuberculosis H37Ra with MIC of 0.5 ug/ml; significantlt reduces bacterial loads of both lungs and spleen in a murine model.Bacterial Infection Preclinical
Synonyms

I 2906;I2906
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

Infection
Indication

Bacterial Infection

CAS Number

331963-29-2
Formula Weight

443.58
Molecular Formula

C25H37N3O4
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CCCCCCCCCCCCC(=O)NNC(=O)C1=C(C2=CC=CC=C2N(C1=O)CC)O
Chemical Name

3-Quinolinecarboxylic acid, 1-ethyl-1,2-dihydro-4-hydroxy-2-oxo-, 2-(1-oxotridecyl)hydrazide

1. Lu J, et al. Pharmacology. 2010;85(6):365-71.

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