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Hypophyllanthin

CAS No. 33676-00-5

Hypophyllanthin( —— )

Catalog No. M24281 CAS No. 33676-00-5

Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 348 In Stock
25MG 573 In Stock
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Biological Information

  • Product Name
    Hypophyllanthin
  • Note
    Research use only, not for human use.
  • Brief Description
    Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
  • Description
    Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
  • In Vitro
    Hypophyllanthin down-regulates COX-2, TNF-α, and IL-1β gene expressions in U937 macrophages by interfering with the activation of NF-κB, MAPKs, and Akt.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel|P-gp|Potassium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    33676-00-5
  • Formula Weight
    430.5
  • Molecular Formula
    C24H30O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (232.29 mM; Need ultrasonic)
  • SMILES
    COC[C@H](Cc1c2)[C@H](COC)[C@@H](c(cc3)cc(OC)c3OC)c1c1OCOc1c2OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cells.J Pharm Pharmacol. 2013 Feb;65(2):292-9.
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