Hydroxybupropion
CAS No. 92264-81-8
Hydroxybupropion ( 6-Hydroxybupropion; Hydroxybupropion, (+/-)-; Hydroxybupropione )
Catalog No. M26253 CAS No. 92264-81-8
Hydroxybupropion is the active metabolite of Bupropion metabolized by CYP2B6. Bupropion is an antidepressant and smoking-cessation agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 158 | Get Quote |
|
5MG | 267 | Get Quote |
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10MG | 417 | Get Quote |
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25MG | 669 | Get Quote |
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50MG | 888 | Get Quote |
|
100MG | 1233 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameHydroxybupropion
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NoteResearch use only, not for human use.
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Brief DescriptionHydroxybupropion is the active metabolite of Bupropion metabolized by CYP2B6. Bupropion is an antidepressant and smoking-cessation agent.
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DescriptionHydroxybupropion is the active metabolite of Bupropion metabolized by CYP2B6. Bupropion is an antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake (IC50: 1.7 μM). Hydroxybupropion is also a nACh receptor antagonist more potent than Bupropion.(In Vitro):Hydroxybupropion shows stronger antitetrabenazine activity and has a lower LD50 value than the erythro- and threo- metabolites. Hydroxybupropion inhibits norepinephrine and dopamine uptake, antagonizes nicotine, and shows antidepressant effects in rodents.
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Synonyms6-Hydroxybupropion; Hydroxybupropion, (+/-)-; Hydroxybupropione
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PathwayOthers
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TargetOther Targets
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RecptorPEGs
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Research Area——
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Indication——
Chemical Information
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CAS Number92264-81-8
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Formula Weight255.7
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Molecular FormulaC13H18ClNO2
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(NC(C)(C)CO)C(=O)c1cccc(Cl)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ohoka N, et al. In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs). J Biol Chem. 2017 Mar 17;292(11):4556-4570.
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