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HyT36
CAS No. 1323151-45-6
HyT36( —— )
Catalog No. M36434 CAS No. 1323151-45-6
HyT36 is a small molecule hydrophobic tag that selectively destabilizes and promotes the degradation of fusion proteins and the pseudokinase Her3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 78 | Get Quote |
|
| 5MG | 116 | Get Quote |
|
| 10MG | 188 | Get Quote |
|
| 25MG | 380 | Get Quote |
|
| 50MG | 609 | Get Quote |
|
| 100MG | 860 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameHyT36
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NoteResearch use only, not for human use.
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Brief DescriptionHyT36 is a small molecule hydrophobic tag that selectively destabilizes and promotes the degradation of fusion proteins and the pseudokinase Her3.
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DescriptionHyT36 is a low molecular weight hydrophobic tag that promotes the degradation of fusion protein and pseudokinase Her3.
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In VitroWestern Blot Analysis Cell Line:HEK293 cells expressing GFP-HaloTag2/Fz4-HaloTag2/HA-EGFP-HaloTag2 or NIH-3T3 cells expressing HA?HaloTag2?HRasG12V.Concentration:1 μM or 10 μM.Incubation Time: 2 h, 24 h or 4 days.Result:Decreased the expression of fusion proteins and increased the binding of Hsp70 and HA-EGFP-HaloTag2 fusion protein.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetHER/HSP
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RecptorHER
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Research Area——
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Indication——
Chemical Information
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CAS Number1323151-45-6
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Formula Weight442.07
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Molecular FormulaC25H44ClNO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (226.21 mM; Ultrasonic )
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SMILESC(C[C@H](C(NCCOCCOCCCCCCCl)=O)C)C12CC3CC(C1)CC(C2)C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tae HS, et al. Identification of hydrophobic tags for the degradation of stabilized proteins. Chembiochem. 2012 Mar 5;13(4):538-41.?
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