Hispidulin

CAS No. 1447-88-7

Hispidulin( —— )

Catalog No. M21669 CAS No. 1447-88-7

Hispidulin a natural flavone with a broad spectrum of biological activities is a Pim-1 inhibitor (IC50: 2.71 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 82 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Hispidulin
  • Note
    Research use only, not for human use.
  • Brief Description
    Hispidulin a natural flavone with a broad spectrum of biological activities is a Pim-1 inhibitor (IC50: 2.71 μM).
  • Description
    Hispidulin a natural flavone with a broad spectrum of biological activities is a Pim-1 inhibitor (IC50: 2.71 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    Pim
  • Recptor
    Pim1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1447-88-7
  • Formula Weight
    300.27
  • Molecular Formula
    C16H12O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 60 mg/mL (199.82 mM; Need ultrasonic);Water: Insoluble
  • SMILES
    COc(c(O)c(c(OC(c(cc1)ccc1O)=C1)c2)C1=O)c2O
  • Chemical Name
    57-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chao SW et al. Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene KinasePim-1. J Nat Prod. 2015 Aug 28;78(8):1969-76.
molnova catalog
related products
  • Quercetagetin

    Quercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).

  • pan-PIM inhibitor 17

    pan-PIM inhibitor 17 is a potent, selective, orally available inhibitor of Pim kinase with IC50 of 0.8, 5.1 and 1.8 nM for Pim1, 2 and 3, respectively.

  • Pim-IN-22m

    Pim-IN-22m is a potent, selective Pim1/Pim2 inhibitor with IC50 of 24/95 pM respectively.