Hederagenin ( Hederagenin; Astrantiagenin E; NSC 24954 )

Catalog No. M18572 CAS No. 465-99-6

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Product Name

Hederagenin
Note

Research use only, not for human use.
Brief Description

Hederagenin is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.
Description

Hederagenin, a triterpenoid saponin, is used to study the properties of triterpenoid saponins as biopesticides that prevent fungal growth, bacterial growth, and viral plant diseases. Hederagenin may be used as a reference in assays to detect it in biological fluids. Hederagenin Supplementation Alleviates the Pro-Inflammatory and Apoptotic Response to Alcohol in Rats.
Synonyms

Hederagenin; Astrantiagenin E; NSC 24954
Pathway

Chromatin/Epigenetic
Target

COX
Recptor

Others
Research Area

Cancer|Neurological Disease
Indication

——

CAS Number

465-99-6
Formula Weight

472.71
Molecular Formula

C30H48O4
Purity

98%
Solubility

DMSO : 50 mg/mL 105.78 mM;
SMILES

C1C(CC[C@@]2(CC[C@]3([C@@]4(CC[C@H]5[C@]([C@H](CC[C@@]5([C@H]4CC=C3[C@H]12)C)O)(C)CO)C)C)C(=O)O)(C)C
Chemical Name

(4aS,6aR,6bS,8aR,9R,10S,12aS,12bR,14bS)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid

1. Lee CW, et al. Int Immunopharmacol. 2015 Dec;29(2):528-37.

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