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HTS07545
CAS No. 118666-03-8
HTS07545( —— )
Catalog No. M35541 CAS No. 118666-03-8
HTS07545 is a potent sulfide:quinone oxidoreductase inhibitor (IC50: 30 nM) that reduces the rate of hydrogen sulfide (H2S) decomposition and has been used in heart failure studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 58 | Get Quote |
|
| 5MG | 85 | Get Quote |
|
| 10MG | 140 | Get Quote |
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| 25MG | 273 | Get Quote |
|
| 50MG | 440 | Get Quote |
|
| 100MG | 618 | Get Quote |
|
| 500MG | 1332 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameHTS07545
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NoteResearch use only, not for human use.
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Brief DescriptionHTS07545 is a potent sulfide:quinone oxidoreductase inhibitor (IC50: 30 nM) that reduces the rate of hydrogen sulfide (H2S) decomposition and has been used in heart failure studies.
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DescriptionHTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM. HTS07545 decrease the rate of breakdown of hydrogen sulfide (H2S). HTS07545 can be used for heart failure research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetNADPH
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RecptorNADPH
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Research Area——
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Indication——
Chemical Information
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CAS Number118666-03-8
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Formula Weight358.39
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Molecular FormulaC22H18N2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (279.03 mM; Ultrasonic )
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SMILESC(#N)C=1C(=CC(=NC1OCC(OCC)=O)C2=CC=CC=C2)C3=CC=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Simon D P Baugh, et al. Synthesis and evaluation of potent novel inhibitors of human sulfide:quinone oxidoreductase. Bioorg Med Chem Lett. 2021 Dec 15;54:128443. ?
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