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HQNO

CAS No. 341-88-8

HQNO( —— )

Catalog No. M22043 CAS No. 341-88-8

HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    HQNO
  • Note
    Research use only, not for human use.
  • Brief Description
    HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III).
  • Description
    HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    mitochondrial NDH-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    341-88-8
  • Formula Weight
    259.34
  • Molecular Formula
    C16H21NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 5 mg/mL (19.28 mM)
  • SMILES
    CCCCCCCC1=CC(=O)C2=CC=CC=C2N1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jessica Petri, et al. Structure of the NDH-2 - HQNO Inhibited Complex Provides Molecular Insight Into Quinone-Binding Site Inhibitors. Biochim Biophys Acta Bioenerg. 2018 Jul;1859(7):482-490.2. Kang J , Kim Y J . HQNO-sensitive NADH:Quinone Oxidoreductase of Bacillus cereus KCTC 3674[J]. J Biochem Mol Biol, 2007, 40(1):53-57.
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